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Answer:
GOMAD
Possible Questions:
Lose it
Snap
Flip
Flip out
Crack up
Freak
Come unglued
Lose one's mind
Descend into dementia
Lose one's marbles
Totally lose it
Lose it and run amok
Flip one's lid
Lose your marbles
Lose touch with reality
Lose control in a way
"If I don't write to empty my mind, I __": Byron